Computing GC Content

AUTHOR

gerdr

http://rosalind.info/problems/gc/

Sample input

>Rosalind_6404
    CCTGCGGAAGATCGGCACTAGAATAGCCAGAACCGTTTCTCTGAGGCTTCCGGCCTTCCC
    TCCCACTAATAATTCTGAGG
    >Rosalind_5959
    CCATCGGTAGCGCATCCTTAGTCCAATTAAGTCCCTATCCAGGCGCTCCGCCGAAGGTCT
    ATATCCATTTGTCAGCAGACACGC
    >Rosalind_0808
    CCACCCTCGTGGTATGGCTAGGCATTCAGGAACCGGAGAACGCTTCAGACCAGCCCGGAC
    TGGGAACCTGCGGGCAGTAGGTGGAAT

Sample output

Rosalind_0808
    60.919540
use v6;



grammar FASTA {
    token TOP { ^ \n* <DNA-string>+ }
    token DNA-string { '>' (\N+) \n (<[ACGT\n]>+) }
}

my $actions = class {
    method TOP($/) {
        make $<DNA-string>>>.ast
    }

    method DNA-string($/) {
        make [~$0, 100 * +.comb(/<[GC]>/) / +.comb(/<[ACGT]>/)]
        given ~$1
    }
};

my $default-input = q:to/END/;
    >Rosalind_6404
    CCTGCGGAAGATCGGCACTAGAATAGCCAGAACCGTTTCTCTGAGGCTTCCGGCCTTCCC
    TCCCACTAATAATTCTGAGG
    >Rosalind_5959
    CCATCGGTAGCGCATCCTTAGTCCAATTAAGTCCCTATCCAGGCGCTCCGCCGAAGGTCT
    ATATCCATTTGTCAGCAGACACGC
    >Rosalind_0808
    CCACCCTCGTGGTATGGCTAGGCATTCAGGAACCGGAGAACGCTTCAGACCAGCCCGGAC
    TGGGAACCTGCGGGCAGTAGGTGGAAT
    END

sub MAIN($input-file = Nil) {
    my $input = $input-file ?? $input-file.IO.slurp !! $default-input;

    FASTA.parse($_, :$actions).ast.sort(*.[1]).[*-1] ~ '%' ==> say()
        given $input;
}

# vim: expandtab shiftwidth=4 ft=perl6

See Also

afrq-grondilu.pl

Counting Disease Carriers

aspc-grondilu.pl

Introduction to Alternative Splicing

cons-grondilu.pl

Consensus and Profile

conv-grondilu.pl

Comparing Spectra with the Spectral Convolution

cstr-grondilu.pl

Creating a Character Table from Genetic Strings

ctbl-grondilu.pl

Creating a Character Table

dbpr-grondilu.pl

Introduction to Protein Databases

dna-gerdr.pl

Counting DNA Nucleotides

dna-grondilu.pl

Counting DNA Nucleotides

eubt-grondilu.pl

Enumerating Unrooted Binary Trees

eval-grondilu.pl

Expected Number of Restriction Sites

fib-grondilu.pl

Rabbits and Recurrence Relations

fibd-grondilu.pl

Mortal Fibonacci Rabbits

grph-grondilu.pl

Overlap Graphs

hamm-grondilu.pl

Counting Point Mutations

iev-grondilu.pl

Calculating Expected Offspring

indc-grondilu.pl

Independent Segregation of Chromosomes

iprb-grondilu.pl

Mendel's First Law

itwv-grondilu.pl

Finding Disjoint Motifs in a Gene

lcsq-grondilu.pl

Finding a Shared Spliced Motif

lia-grondilu.pl

Independent Alleles

lrep-grondilu-p5.pl

mmch-grondilu.pl

Maximum Matchings and RNA Secondary Structures

mprt-grondilu.pl

Finding a Protein Motif

mrna-grondilu.pl

Inferring mRNA from Protein

nwck-grondilu.pl

Distances in Trees

orf-grondilu.pl

Open Reading Frames

pmch-grondilu.pl

Perfect Matchings and RNA Secondary Structures

pper-grondilu.pl

Partial Permutations

prob-grondilu.pl

Introduction to Random Strings

qrt-grondilu.pl

Quartets

README.md

revc-gerdr.pl

Complementing a Strand of DNA

rna-gerdr.pl

Transcribing DNA into RNA

rstr-grondilu.pl

Matching Random Motifs

sexl-grondilu.pl

Sex-Linked Inheritance

sgra-grondilu.pl

Using the Spectrum Graph to Infer Peptides

spec-grondilu.pl

Inferring Protein from Spectrum

sseq-grondilu.pl

Finding a Spliced Motif

subs-grondilu.pl

Finding a Motif in DNA

suff-grondilu.pl

Encoding Suffix Trees

tran-grondilu.pl

Transitions and Transversions

trie-grondilu.pl

Introduction to Pattern Matching

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